Comparison of Intra-articular Platelet Rich Plasma versus Corticosteroid Injections for the Treatment of Moderate Knee Osteoarthritis

Objective: To compare the efficacy of intra-articular injections prednisolone acetate and platelet rich plasma in cases moderate knee osteoarthritis. Study design: Prospective comparative study. Place Duration study: Department Orthopedic Surgery, Khairpur Medical College, Mirs, from January 2021 till December Methodology: A total 100 patients were selected for study randomly divided into two equal groups. Group C received corticosteroid injection along with local anesthetic (Prednisolone 40 mg + 3 ml 0.5% bupivacaine) under ultrasound guidance. P PRP, each 8 volume given at one week’s interval. Patients signs hemodynamic compromise, sepsis, past history any same joint also excluded Follow up was carried out 1, 6 months. The Western Ontario McMaster Universities Osteoarthritis (WOMAC) scale used to assess prior then follow up. WOMAC consists three subsets i-e pain, stiffness physical function. Results: Demographic data comparable between both Pre-injection score group 71.54±12.18 75.20±8.58 respectively (p-value=0.086); after month injections, it 34.20±10.48 35.38±6.31 (p-value=0.580). After months injection, 33.20±8.13 31.10±5.50 (p-value=0.195). 35.32±10.41 32.10±6.63 (p-value=0.68). Conclusion: It is concluded our that PRP are equally effective